Description

Ketamine is a general anesthetic agent used for diagnostic and surgical procedures. However, the typical concentration of ketamine hydrochloride injection is 50 mg/mL or 100 mg/mL, not 500 mg in 10 mL. Here’s an overview based on standard formulations:

Composition

• Active Substance: Ketamine hydrochloride, equivalent to ketamine base.

• Concentration: Commonly available as 50 mg/mL or 100 mg/mL solutions.

Indications

• Anesthesia: Used as the sole anesthetic agent for procedures not requiring skeletal muscle relaxation.

• Induction of Anesthesia: Prior to other general anesthetic agents.

• Supplement to Other Anesthetics: To enhance the effects of low-potency agents.

Dosage

• Intravenous Induction: 1 to 4.5 mg/kg administered slowly over 60 seconds.

• Intramuscular Induction: 6.5 to 13 mg/kg.