Teriseba Insulin Pen 1’ct Imported India
Teriseba Insulin Pen 1’ct Imported India is likely a misspelling or incorrect name for Tresiba Insulin Degludec Flex Touch Pen, a long-acting insulin product used to treat diabetes. The correct name is Tresiba, not Teriseba.Tresiba Insulin Degludec Flex Touch Pen is available in a 1’ct (1 count) package and is imported into India. It is a long-acting basal insulin that helps control blood sugar levels in adults with diabetes.The Tresiba FlexTouch pen is compatible with most universal fit needles, and NovoFine Plus 32G Tip needles are recommended as they are one of the shortest and thinnest available. The pen delivers accurate doses up to 160 units in 1 unit increments and contains 600 total units.Tresiba should be injected subcutaneously once daily at the same time each day. Injection sites should be rotated to prevent lipodystrophy. Opened pens can be used for up to 4 weeks at room temperature, while unopened pens should be refrigerated
Description
Teriseba Insulin Pen 1’ct Imported India is likely a misspelling or incorrect name for Tresiba Insulin Degludec Flex Touch Pen, a long-acting insulin product used to treat diabetes. The correct name is Tresiba, not Teriseba.Tresiba Insulin Degludec Flex Touch Pen is available in a 1’ct (1 count) package and is imported into India. It is a long-acting basal insulin that helps control blood sugar levels in adults with diabetes.The Tresiba FlexTouch pen is compatible with most universal fit needles, and NovoFine Plus 32G Tip needles are recommended as they are one of the shortest and thinnest available. The pen delivers accurate doses up to 160 units in 1 unit increments and contains 600 total units.Tresiba should be injected subcutaneously once daily at the same time each day. Injection sites should be rotated to prevent lipodystrophy. Opened pens can be used for up to 4 weeks at room temperature, while unopened pens should be refrigerated
Ultra-Long-Acting Insulin
- Tresiba is an ultra-long-acting basal insulin that provides up to 42 hours of consistent blood sugar control with a single daily injection.
- This extended duration of action helps provide stable and predictable blood glucose levels throughout the day and night.
Flexible Dosing
- The Tresiba FlexTouch pen allows for flexible once-daily dosing at any time of day that is most convenient for the patient.
- Doses can be adjusted in 1 unit increments up to 160 units per injection, providing precise dosing control.
Needle-Free Injection
- The FlexTouch pen uses a spring-loaded mechanism to deliver insulin with minimal force, allowing for a virtually painless injection experience.
- The pen also has a large, easy-to-read dose window for clear visibility of the set dose.
Durability and Convenience
- Tresiba insulin pens can be used for up to 8 weeks after first use, reducing the need for frequent pen replacements.
- The pens are also designed to be more durable, with a reinforced outer shell to withstand drops and bumps.
Reduced Hypoglycemia Risk
- Clinical studies have shown that Tresiba has a lower risk of overall, nocturnal, and severe hypoglycemia compared to other basal insulins.
- This can provide greater peace of mind and improved glycemic control for patients.
Key Benefits
- Ultra-long-acting insulin that provides up to 42 hours of consistent blood sugar control with a single daily injection
- Flexible once-daily dosing at any time that is convenient for the patient
- Precise dosing control with adjustments in 1 unit increments up to 160 units per injection
- Virtually painless injection experience due to the spring-loaded, needle-free delivery mechanism
- Durable pen design that can be used for up to 8 weeks after first use
- Lower risk of overall, nocturnal, and severe hypoglycemia compared to other basal insulins
Key Ingredient
- The active ingredient in Tresiba is insulin degludec, a long-acting basal insulin that helps control blood sugar levels in adults with diabetes
Overall, the Tresiba Insulin Degludec Flex Touch Pen offers a unique combination of ultra-long-acting efficacy, flexible dosing, and improved injection experience that can benefit many patients with diabetes. The mechanism of action of Tresiba (insulin degludec) is as follows:Tresiba is a long-acting basal insulin that lowers blood glucose levels by stimulating peripheral glucose uptake, especially by skeletal muscle and adipose tissue. It also reduces hepatic glucose production.The unique molecular design of insulin degludec allows it to form soluble multi-hexamers upon subcutaneous injection, creating a depot from which insulin is slowly and continuously released, resulting in a flat and stable glucose-lowering effect with a duration of action beyond 24 hours.Specifically, after injection, the insulin degludec molecules form dihexamers in the presence of zinc and phenol. When injected into the subcutaneous tissue, the phenol diffuses away, allowing the dihexamers to form long multi-hexameric chains. Zinc then slowly diffuses away, releasing insulin monomers from the ends of the chains. This results in a stable and continuous delivery of insulin into the circulation over 24 hours or more.
Based on the search results, here is the information on the chemical structure of insulin degludec, the active ingredient in the Tresiba Insulin Pen:
Chemical Structure of Insulin Degludec
Insulin degludec has the following chemical structure:
- Molecular formula: C274H411N65O81S6
- Molecular weight: 6103.97 g/mol
- It is a modified insulin molecule that has one single amino acid deleted compared to human insulin.
- Insulin degludec is conjugated to hexadecanedioic acid via a gamma-L-glutamyl spacer at the amino acid lysine at position B29.
The structural formula of insulin degludec is shown in Figure 1 of the Tresiba prescribing information :Structural Formula of Tresiba (Insulin Degludec)This unique chemical structure of insulin degludec provides the ultra-long-acting profile and stable glucose-lowering effect of the Tresiba insulin pen. The conjugation to hexadecanedioic acid allows insulin degludec to form soluble multi-hexamers upon subcutaneous injection, creating a depot from which insulin is slowly and continuously released over 24 hours or more.
Dosage
Starting Dose
- For insulin-naïve patients with type 1 diabetes, the recommended starting dose is 0.2-0.4 units/kg, with the remainder of the total daily insulin dose administered as short-acting insulin.
- For insulin-naïve patients with type 2 diabetes, the recommended starting dose is 10 units once daily.
Dosage Adjustments
- When switching to Tresiba from other insulin therapies, the starting Tresiba dose should be the same as the total daily long-acting or intermediate-acting insulin dose.
- Doses can be adjusted in 1 unit increments for the U-100 pen or 2 unit increments for the U-200 pen, up to a maximum of 160 units per injection.
Storage
Unopened (Unused) Pens
- Unopened Tresiba pens should be stored in a refrigerator between 36°F to 46°F (2°C to 8°C).
- Unopened pens can also be stored at room temperature up to 86°F (30°C) for up to 56 days.
In-Use (Opened) Pens
- After first use, opened Tresiba pens can be stored at room temperature up to 86°F (30°C) or in the refrigerator for up to 8 weeks (56 days).
- Do not freeze Tresiba and do not use it if it has been frozen.
Reviews
Clinical studies have shown that Tresiba provides:
- Ultra-long-acting insulin delivery for up to 42 hours with a single daily injection
- Lower risk of overall, nocturnal, and severe hypoglycemia compared to other basal insulins
- Flexible once-daily dosing at any time that is convenient for the patient
Reviews
There are no reviews yet.