Description

Darzalex (daratumumab) 100 mg/5 mL Injection

• Prescription medicine used to treat multiple myeloma
• Intravenous (IV) infusion administered by a healthcare provider
• 100 mg/5 mL dosage form supplied in single-dose vials
• Colorless to pale yellow, preservative-free solution
• Works by targeting CD38 protein on myeloma cells
• Dosage depends on whether used alone or with other drugs
• Typically given weekly, every 3 weeks, or every 4 weeks
• Must be diluted before administration
• Stored refrigerated and protected from light
  

  Key Benefits:

  • Treats multiple myeloma, a type of blood cancer
  • Effective as monotherapy or in combination with other drugs for newly diagnosed or relapsed/refractory multiple myeloma
  • Also approved for treating light chain (AL) amyloidosis, a rare blood disease

  Key Ingredients:

  • Active ingredient: Daratumumab, a human monoclonal antibody that targets the CD38 protein on multiple myeloma cells
  • Other ingredients: Glacial acetic acid, mannitol, polysorbate 20, sodium acetate trihydrate, sodium chloride, and water for injection

  The key mechanism of action is that Darzalex binds to the CD38 protein on the surface of multiple myeloma cells, triggering immune-mediated tumor cell lysis and apoptosis (cell death) through various cytotoxic pathways.Darzalex is administered as an intravenous (IV) infusion and must be diluted with 0.9% sodium chloride injection before administration. The dosage and frequency depends on whether it is used alone or in combination with other multiple myeloma treatments.

  Dosage

  • IV infusion, dosage depends on use as monotherapy or combination
  • Typical schedules: weekly for 8 weeks, then every 2 weeks for 16 weeks, then every 4 weeks
  • Requires dilution before administration

  Storage

  • Refrigerate vials at 2-8°C, protect from light
  • Unopened vials may be stored at room temp up to 30°C for 24 hours
  • Diluted solution stable refrigerated for 24 hours and/or at room temp for 15 hours

  Reviews

  • No patient review information available
  • Approved for multiple myeloma and AL amyloidosis based on clinical trials

  Order site

  Vitamins collection.com

  Contact

  0307-7532291/0320-6421093