Eltroxin 50mg 100’ct tablets
Indications:
Eltroxin (levothyroxine) is primarily used for the treatment of hypothyroidism, a condition characterized by an underactive thyroid gland.
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Description
Eltroxin 50 mcg Tablet is a medication used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones.Key points:
- Eltroxin 50 mcg Tablet contains the active ingredient levothyroxine sodium, which is a synthetic version of the thyroid hormone thyroxine.
- It is used to replace the low levels of thyroid hormone in people with hypothyroidism, which can cause symptoms like fatigue, weight gain, sensitivity to cold, and muscle weakness.
- The recommended starting dose for adults is 50-100 mcg daily, which is then adjusted based on blood tests to reach the target thyroid hormone levels.
- Eltroxin 50 mcg Tablet should be taken on an empty stomach, preferably 30 minutes to 1 hour before breakfast, with a full glass of water.
- Certain medications like antacids, iron supplements, and cholestyramine can interfere with the absorption of Eltroxin, so it’s important to take it separately from these drugs.
- Regular monitoring of thyroid function is required to ensure the appropriate dosage is maintained.
- Eltroxin 50 mcg Tablet should not be used for weight loss or obesity, as it is only indicated for the treatment of hypothyroidism.
Brand Name and Manufacturer
Eltroxin is the brand name for levothyroxine sodium tablets manufactured by GlaxoSmithKline (GSK). It is one of the most well-known and widely prescribed brands of levothyroxine worldwide.
Tablet Composition
Each Eltroxin 50 mcg tablet contains 50 micrograms of levothyroxine sodium as the active ingredient. The tablets also contain the following inactive ingredients:
- Lactose monohydrate
- Maize starch
- Gelatin
- Croscarmellose sodium
- Magnesium stearate
- Sucrose
- Acacia
- Talc
- Titanium dioxide (E171)
- Quinoline yellow (E104)
Unique Packaging
Eltroxin 50 mcg tablets are available in unique blister packs containing 100 tablets. This large pack size is convenient for patients who require long-term treatment for hypothyroidism.
Strict Manufacturing Standards
As a leading pharmaceutical company, GSK adheres to strict manufacturing standards and quality control measures to ensure the consistency and purity of Eltroxin tablets. The manufacturing process is carried out in compliance with Good Manufacturing Practices (GMP) guidelines.
Extensive Clinical Experience
Eltroxin has been available for many years and has a well-established safety and efficacy profile based on extensive clinical experience in the treatment of hypothyroidism. It is one of the most widely prescribed and trusted brands of levothyroxine worldwide.
Regulatory Approvals
Eltroxin 50 mcg tablets have been approved for use in many countries around the world, including the United States, Canada, and various European countries, ensuring its quality and safety for patient use                                                     Key Benefits:
- Treats hypothyroidism by replacing deficient thyroid hormones
- Restores normal metabolic functions and addresses related symptoms
- Convenient 100-tablet pack size for long-term use
- Manufactured under strict quality standards by GlaxoSmithKline
- Extensive clinical experience and established safety profile
Key Ingredients:
- Active ingredient: Levothyroxine sodium
- Excipients: Lactose monohydrate, maize starch, gelatin, croscarmellose sodium, magnesium stearate, sucrose, acacia, talc, titanium dioxide, and quinoline yellow
key points about the mechanism of action of Eltroxin (levothyroxine sodium) 50 mcg Tablets are:
- Eltroxin contains the active ingredient levothyroxine sodium, which is a synthetic version of the thyroid hormone thyroxine.
- The thyroid gland naturally produces two active thyroid hormones – levothyroxine (T4) and triiodothyronine (T3). Levothyroxine is the predominant hormone produced.
- The chief action of levothyroxine is to increase the rate of cell metabolism throughout the body. It helps restore normal metabolic functions that are slowed down due to hypothyroidism.
- Levothyroxine is deiodinated in peripheral tissues to form triiodothyronine (T3), which is thought to be the more active form of the thyroid hormone.
- Triiodothyronine (T3) is more rapid acting and has a shorter duration of action compared to levothyroxine (T4).
- Levothyroxine is incompletely and variably absorbed from the gastrointestinal tract. It is almost completely bound to plasma proteins and has a half-life of about a week in healthy individuals.
- A large portion of the levothyroxine leaving the circulation is taken up by the liver, where part of the dose is metabolized to triiodothyronine.
- Levothyroxine is excreted in the urine as free drug, deiodinated metabolites, and conjugates. Some is also excreted in the feces.
LevothyroxineSynthetic thyroid hormone medicationMoreTrade namesSynthroid, Levoxyl, Thyrax, othersUsed forTreatment of hypothyroidism, myxedema coma, and certain thyroid tumorsAdministrationOral or intravenousBased on the search results, the key information about the chemical structure of Eltroxin (levothyroxine sodium) is:
- Molecular Formula: C15H10I4NNaO4
- Molecular Weight: 798.86 g/mol
- The chemical name is levothyroxine sodium, which is the sodium salt of the thyroid hormone levothyroxine (T4).
- Levothyroxine sodium is the active ingredient in Eltroxin tablets.
- Levothyroxine sodium is a white to pale brownish-yellow, odorless crystalline powder.
- The structural formula of levothyroxine sodium is:
Levothyroxine sodium structural formula
- Levothyroxine sodium is highly lipophilic and is almost completely bound to plasma proteins in the body.
Dosage:
- Start at 50-100 mcg daily, taken on an empty stomach
- Adjust dose gradually based on blood tests to reach target levels
- Max dose is typically 50-200 mcg daily
Storage:
- Store below 25°C in original package
- Keep out of reach of children
- Do not use after expiry date
Reviews:
- Well-established brand with extensive safety and efficacy profile
- Generally effective in controlling hypothyroidism symptoms
- Some common side effects like appetite changes, hair loss, headaches
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