Description

Femara 2.5 mg tablet is a prescription medication used to treat breast cancer in postmenopausal women. The active ingredient in Femara is letrozole, which belongs to a class of drugs called nonsteroidal aromatase inhibitors. Femara works by reducing estrogen production in the body, which can help slow the growth of breast cancer cells that rely on estrogen.Femara 2.5 mg tablet is most commonly used to treat postmenopausal women with hormone-dependent breast cancer. It can help treat breast cancer and prevent it from recurring. The recommended dose is 2.5 mg taken once daily, and no dose adjustment is necessary for elderly patients.Some key risks and warnings associated with Femara include:

• Letrozole should not be taken during pregnancy as it can harm the fetus.
• Breastfeeding is prohibited during Femara treatment, but can resume 3 weeks after finishing therapy.
• Letrozole can cause dizziness and blurred vision, so caution is advised when driving.
• Patients with liver or kidney disease should consult their doctor before taking Femara.
• Those allergic to letrozole or any Femara ingredients should not use this medication.
  

  Mechanism of Action

  Femara (letrozole) is a highly selective nonsteroidal aromatase inhibitor. It works by blocking the aromatase enzyme, which is responsible for the production of estrogen in postmenopausal women. This helps reduce estrogen levels and slow the growth of hormone-dependent breast cancer.

  Indication and Approved Uses

  Femara 2.5 mg tablets are approved by the FDA for the following uses in postmenopausal women:

  • Adjuvant treatment of early breast cancer
  • First-line treatment of advanced breast cancer
  • Extended adjuvant treatment of early breast cancer

  Femara is unique in that it is one of the few aromatase inhibitors approved for all these different breast cancer treatment settings.

  Dosing and Administration

  Femara is taken orally as a single 2.5 mg tablet once daily, with or without food. This once-daily dosing is convenient for patients compared to some other aromatase inhibitors.

  Clinical Efficacy

  Clinical studies have shown Femara to be highly effective in improving outcomes for postmenopausal women with hormone-receptor positive breast cancer. It has demonstrated superior efficacy compared to tamoxifen in several large trials.

  Safety Profile

  Femara has a well-established safety profile, with the most common side effects being hot flashes, arthralgia, fatigue, and dizziness. It does not carry the increased risk of thromboembolic events associated with some other breast cancer therapies.

  Key Ingredient

  The active ingredient in Femara 2.5 mg tablets is letrozole. Letrozole is a nonsteroidal aromatase inhibitor, which means it blocks the aromatase enzyme responsible for converting androgens into estrogens in the body.

  Key Benefits

  The key benefits of Femara 2.5 mg tablets include:

  1. Treatment of hormone receptor-positive breast cancer in postmenopausal women:
     • Femara is approved for adjuvant (after surgery), extended adjuvant, first-line, and advanced/metastatic treatment of hormone-dependent breast cancer in postmenopausal women.
     • Clinical studies have shown Femara to be highly effective in improving outcomes for these patients compared to other therapies.
  2. Reduction of estrogen levels:
     • By inhibiting the aromatase enzyme, Femara reduces the production of estrogen in the body.
     • This helps slow the growth of hormone-dependent breast cancer cells that rely on estrogen for growth.
  3. Convenient once-daily oral dosing:
     • Femara is taken as a single 2.5 mg tablet once daily, which is a convenient dosing regimen for patients.
  4. Favorable safety profile:
     • Femara has a well-established safety profile, with the most common side effects being manageable.
     • It does not carry the increased risk of thromboembolic events associated with some other breast cancer therapies.                                                                                                          The key mechanism of action for Femara (letrozole) 2.5 mg tablets is:       Femara is a highly selective nonsteroidal aromatase inhibitor. It works by blocking the aromatase enzyme, which is responsible for the conversion of androgens into estrogens in the body. By inhibiting this enzyme, Femara reduces estrogen production, which helps slow the growth of hormone-dependent breast cancer cells that rely on estrogen for proliferation.Specifically, letrozole binds to the heme group of the aromatase enzyme, inhibiting its activity and reducing estrogen biosynthesis. This mechanism of action is what makes Femara effective in treating hormone receptor-positive breast cancer in postmenopausal women.
       

       Letrozole

       Aromatase inhibitor medication for breast cancer treatment

       More
       Description

       Letrozole, marketed under the brand name Femara among others, is used in the treatment of breast cancer.

       Approval Year

       Patented in 1986 and approved for medical use in 1996.

       Prescription Frequency

       In 2020, it was the 257th most commonly prescribed medication in the United States with over 1 million prescriptions.

       Storage of Femara 2.5 mg

       • Store at room temperature, away from heat, moisture and light
       • Keep out of reach of children and pets

       Reviews

       No specific reviews available in the provided information. Femara has been shown effective for hormone-positive breast cancer in postmenopausal women in studies, but real-world patient experiences are not included.Patients should take Femara as directed and follow storage guidelines. Consult a doctor for any questions.

       Conclusion: Femara 2.5 mg Tablets

       In conclusion, Femara (letrozole) 2.5 mg tablets are a prescription medication used to treat hormone receptor-positive breast cancer in postmenopausal women.                                   Order site                                                                                                                         Vitamins collection.com                                                                                                  Contact                                                                                                                                0307-7532291/0320-6421093