Description

Azacitidine 100 mg Injection is a medication used to treat certain types of blood cancers, specifically myelodysplastic syndrome (MDS) and juvenile myelomonocytic leukemia (JMML). It works by helping the bone marrow produce healthy blood cells and killing abnormal blood cells that have grown too fast.The key points about Azacitidine 100 mg Injection are:

• It is given by injection under the skin or into a vein, usually once a day for 7 days in a row, with this 7-day cycle repeated every 4 weeks.
• Common side effects include redness/pain/bruising at the injection site, tiredness, diarrhea, nausea, vomiting, and mouth sores. More serious side effects like easy bleeding/bruising, infections, and allergic reactions can also occur.
• Azacitidine is contraindicated in patients with advanced malignant hepatic tumors.
• Patients should be monitored closely by their doctor, and the dosage may need to be adjusted based on response and side effects.
• Azacitidine should not be used during pregnancy as it can harm the developing fetus. Effective birth control is recommended for both male and female patients.                                Azacitidine 100 mg Injection does not have any key ingredients listed, as it is a single-ingredient medication. The key benefit of Azacitidine 100 mg Injection is that it helps treat certain types of blood cancers, specifically myelodysplastic syndrome (MDS) and juvenile myelomonocytic leukemia (JMML).Azacitidine works by:
  • Helping the bone marrow produce healthy blood cells
  • Killing abnormal blood cells that have grown too fast and do not work properly
  • Interfering with the cell’s DNA synthesis and decreasing growth and multiplication of cancer cells

  By doing this, Azacitidine can improve blood cell counts and reduce symptoms in patients with MDS and JMML                                                                                                                                     Dosage:

  • 75 mg/m2 subcutaneously or intravenously daily for 7 days for first cycle
  • Dose may be increased to 100 mg/m2 if no benefit after 2 cycles
  • Treat for minimum 4-6 cycles, adjust dose based on response and toxicity

  Storage:

  • Supplied as 100 mg lyophilized powder in single-dose vials
  • Reconstituted IV solution stable for 1 hour at 25°C

  Reviews:

  • Effective for myelodysplastic syndrome and acute myeloid leukemia
  • Common side effects include nausea, fatigue, rashes, injection site reactions
  • Serious side effects like infections, bleeding require monitoring