Lipitor (Atorvastatin) 40mg 30’ct tablet
Lipitor 40mg film-coated tablets are used to lower high cholesterol levels in adults and children aged 10 years or older. Each tablet contains 40 mg of atorvastatin, the active ingredient which reduces LDL (bad) cholesterol production and increases LDL receptor activity.The recommended starting dose is 10 mg once daily, with adjustment at 4-week intervals up to a maximum of 80 mg once daily. Patients requiring an LDL-C reduction greater than 45% may be started at 40 mg once daily.Lipitor 40mg tablets are white, round, 9.5 mm in size, and debossed with “40” on one side and “ATV” on the other. They are supplied in bottles of 90 tablets.Common side effects may include muscle pain, weakness, and injury, especially in those aged 65 and older. Atorvastatin should not be used in those with liver problems or allergies to any of its ingredients
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Description
Active Ingredient
Each film-coated tablet contains 40 mg of atorvastatin, a cholesterol-lowering medication.
Dosage
The recommended starting dose is 10 mg once daily, with adjustment at 4-week intervals up to a maximum of 80 mg once daily. Patients requiring an LDL-C reduction greater than 45% may be started at 40 mg once daily.
Physical Characteristics
The tablets are white, round, 9.5 mm in size, and debossed with “40” on one side and “ATV” on the other.
Packaging
Lipitor 40mg tablets are supplied in bottles of 90 tablets.
Excipients
The tablets contain excipients such as lactose monohydrate and benzoic acid.
Manufacturer
Pfizer Manufacturing Deutschland GmbH in Germany manufactures the tablets.
Key Benefits of Lipitor 40mg Tablets
- Lowers elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia
- Reduces total cholesterol and LDL-cholesterol in adults with homozygous familial hypercholesterolaemia
- Prevents cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event
Key Ingredients
Each Lipitor 40mg film-coated tablet contains:
- 40 mg atorvastatin (as atorvastatin calcium trihydrate) as the active ingredient
- Excipients such as 109.00 mg lactose monohydrate and 0.00016 mg benzoic acid
The tablets are white, round, 9.5 mm in size, and debossed with “40” on one side and “ATV” on the other.
Mechanism of Action of Lipitor (Atorvastatin)
Lipitor (atorvastatin) is a statin medication that works by inhibiting the activity of an enzyme called HMG-CoA reductase, which is involved in the production of cholesterol in the body. Specifically:Inhibition of HMG-CoA Reductase
- Atorvastatin competitively inhibits the HMG-CoA reductase enzyme, which is the rate-limiting step in cholesterol biosynthesis.
- By blocking this enzyme, atorvastatin reduces the production of cholesterol, particularly low-density lipoprotein (LDL) cholesterol, in the liver.
Increased LDL Receptor Activity
- Atorvastatin also increases the number of hepatic LDL receptors on the cell surface, enhancing the uptake and catabolism of LDL cholesterol from the blood.
Reduced Triglyceride Levels
- In addition, atorvastatin reduces triglyceride levels and increases high-density lipoprotein (HDL) cholesterol to a lesser extent.
Through these mechanisms, atorvastatin is effective at lowering elevated levels of total cholesterol, LDL cholesterol, and triglycerides, while also increasing HDL cholesterol levels. This helps reduce the risk of cardiovascular events in patients with high cholesterol or at risk of heart disease.
Dosage of Lipitor 40mg Tablets
- The recommended starting dose is 10 mg once daily, with adjustment at 4-week intervals up to a maximum of 80 mg once daily.
- Patients requiring an LDL-C reduction greater than 45% may be started at 40 mg once daily.
- Lipitor should be taken once daily at any time of the day, with or without food.
- If a dose is missed, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule.
Storage
- Store Lipitor 40mg tablets below 25°C in a cool and dry place.
- Keep the tablets out of the reach of children.
- Discard any unused medicine properly.
Reviews
Lipitor 40mg tablets are generally well-tolerated, with common side effects including:
- Mild muscle pain and joint pain
- Diarrhea
- Nausea
- Urinary tract infection (UTI)
- Pain in hands or feet
- Upper respiratory infection
Rare but serious side effects may include severe muscle problems, especially if accompanied by general discomfort or fever. Contact your doctor if you experience unusual muscle aches or weakness.
Reviews
There are no reviews yet.