Lipitor (Atorvastatin) 40mg 30’ct tablet
Lipitor (atorvastatin) 40mg tablets are a prescription medication used to lower bad cholesterol (LDL-C) and triglyceride levels in the blood, while increasing good cholesterol (HDL). This helps decrease the risk of heart disease, stroke, and heart attack.Each Lipitor 40mg tablet contains atorvastatin calcium trihydrate equivalent to 40mg of atorvastatin. The recommended dosage range is 10mg to 80mg once daily. Patients who require an LDL-C reduction greater than 45% may be started at 40mg once daily.Lipitor 40mg tablets are white, round, film-coated tablets marked with ’40’ on one side and ‘ATV’ on the other. They are supplied in blister packs of 10 and 30 tablets.Lipitor should be stored at controlled room temperature between 20-25°C (68-77°F). The oral suspension should be used within 60 days of opening.
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Description
Facts About Lipitor (Atorvastatin) 40mg Tablets
1. Best-Selling Drug of All Time
Lipitor was the best-selling drug of all time, generating over $125 billion in revenue for Pfizer before going generic in 2011.
2. Most Potent Statin
Atorvastatin is the most potent statin, able to lower LDL cholesterol by up to 55% at the maximum 80mg dose.
3. Most Commonly Prescribed Dose
The 40mg dose is the most commonly prescribed dose of Lipitor. It provides a good balance of efficacy and tolerability for most patients.
4. Promotes Plaque Regression
Lipitor was the first statin shown to not only slow the progression of atherosclerosis, but also promote regression of plaque buildup in the arteries.
5. Additional Cardiovascular Benefits
In addition to its cholesterol-lowering effects, Lipitor has anti-inflammatory and antioxidant properties that may provide additional cardiovascular benefits.
6. Flexible Dosing
Lipitor is one of the few statins that can be taken at any time of day, with or without food, due to its long half-life.
7. Metabolism Considerations
Atorvastatin is metabolized by the CYP3A4 enzyme in the liver. Certain drugs that inhibit this enzyme can increase atorvastatin levels and risk of side effects.
8. Approved for Pediatric Use
Lipitor is approved for use in children and adolescents aged 10-17 years with heterozygous familial hypercholesterolemia
Key Benefits of Lipitor (Atorvastatin) 40mg Tablets
- Lowers LDL (“bad”) cholesterol levels by up to 55% at the maximum 80mg dose, making it the most potent statin medication.
- Increases HDL (“good”) cholesterol levels, which helps remove plaque buildup in the arteries.
- Reduces the risk of heart attack, stroke, chest pain, and the need for certain heart surgeries in adults with high cholesterol or cardiovascular disease.
- Can be used to treat high cholesterol in children and adolescents aged 10-17 years with familial hypercholesterolemia.
- Provides anti-inflammatory and antioxidant effects that may offer additional cardiovascular benefits beyond just lowering cholesterol.
Key Ingredients
The active ingredient in Lipitor 40mg tablets is atorvastatin calcium trihydrate, equivalent to 40mg of atorvastatin. Atorvastatin is a member of the statin class of cholesterol-lowering medications.The inactive ingredients include:
- Calcium carbonate
- Croscarmellose sodium
- Hydroxypropyl cellulose
- Lactose monohydrate
- Magnesium stearate
- Microcrystalline cellulose
- Polysorbate 80
- Talc
- Titanium dioxide
These inactive ingredients serve various functional purposes such as binding, disintegrating, and coating the tablet.
Dosage of Lipitor (Atorvastatin) 40mg Tablets
- The recommended starting dose is 10-20mg once daily.
- Patients who require an LDL-C reduction greater than 45% may be started at 40mg once daily.
- The dosage range is 10-80mg once daily.
- Lipitor can be taken at any time of day, with or without food.
Storage of Lipitor 40mg Tablets
- Store at controlled room temperature between 20-25°C (68-77°F).
- Keep out of reach of children.
- Discard any unused medicine properly.
- The oral suspension should be used within 60 days of opening.
Reviews of Lipitor 40mg Tablets
Lipitor is a highly effective medication for lowering LDL cholesterol and reducing the risk of cardiovascular events in high-risk patients. It is generally well-tolerated, with the most common side effects being headache, nausea, diarrhea, and muscle pain.The 40mg dose provides a good balance of efficacy and tolerability for most patients. Atorvastatin is the most potent statin, able to lower LDL by up to 55% at the maximum 80mg dose.Lipitor has been shown to not only slow the progression of atherosclerosis, but also promote regression of plaque buildup in the arteries. It has additional anti-inflammatory and antioxidant properties that may provide further cardiovascular benefits.
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