Description

Methadone is a synthetic opioid medication primarily used for managing severe chronic pain and treating opioid use disorder. The 40 mg formulation is specifically indicated for the detoxification and maintenance treatment of opioid addiction, not for pain management.

Key Points

• Indications: The 40 mg methadone formulation is used for detoxification and maintenance treatment of opioid addiction. It is not FDA-approved for pain management4.

• Distribution: Due to its use in opioid addiction treatment, the distribution of the 40 mg formulation is restricted to authorized facilities, such as those involved in opioid treatment programs4.

• Mechanism of Action: Methadone works by activating opioid receptors in the brain and nervous system, reducing pain perception and withdrawal symptoms26.

• Side Effects: Common side effects include constipation, nausea, dizziness, and respiratory depression. Serious side effects may include QT interval prolongation and torsades de pointes, particularly at higher doses