Description

Nicorette Fruitfusion 2mg Lozenges are a nicotine replacement therapy (NRT) product designed to help individuals quit smoking. These lozenges contain nicotine, which can help relieve withdrawal symptoms and cravings when trying to stop smoking.The lozenges are available in the UK and can be purchased in Pakistan. They are a form of NRT that provides a controlled dose of nicotine through the lining of the mouth as the lozenge dissolves, without the harmful chemicals found in tobacco smoke.Nicorette Fruitfusion lozenges come in a 2mg strength, which is recommended for those who smoke 20 or fewer cigarettes per day. A higher 4mg strength is also available for heavier smokers.To use the lozenges, you should place one in your mouth and allow it to slowly dissolve, moving it around occasionally. This allows the nicotine to be absorbed through the lining of your mouth. The lozenges can be used as needed to help manage cravings and withdrawal symptoms when trying to quit smoking.

Product Overview

• Nicorette Fruitfusion 2mg Lozenges are a nicotine replacement therapy (NRT) product designed to help people quit smoking.
• These lozenges contain nicotine, which can help relieve withdrawal symptoms and cravings when trying to stop smoking.

Availability in Pakistan

• The Nicorette Fruitfusion lozenges are available in the UK and can be purchased in Pakistan.
• They are a form of NRT that provides a controlled dose of nicotine through the lining of the mouth as the lozenge dissolves.

Nicotine Strength

• The Nicorette Fruitfusion lozenges come in a 2mg strength, which is recommended for those who smoke 20 or fewer cigarettes per day.
• A higher 4mg strength is also available for heavier smokers.

Usage Instructions

• To use the lozenges, you should place one in your mouth and allow it to slowly dissolve, moving it around occasionally.
• This allows the nicotine to be absorbed through the lining of your mouth and can help manage cravings and withdrawal symptoms when trying to quit smoking.

Key Benefits of Nicorette Fruitfusion 2mg Lozenges

Nicotine Replacement Therapy

• The Nicorette Fruitfusion 2mg lozenges are a form of nicotine replacement therapy (NRT) that can help relieve withdrawal symptoms and cravings when trying to quit smoking.

Controlled Nicotine Delivery

• The lozenges provide a controlled dose of nicotine that is absorbed through the lining of the mouth as the lozenge dissolves, without the harmful chemicals found in tobacco smoke.

Suitable for Light Smokers

• The 2mg strength is recommended for those who smoke 20 or fewer cigarettes per day. A higher 4mg strength is available for heavier smokers.

Helps Manage Cravings

• Using the lozenges can help manage cravings and withdrawal symptoms when trying to quit smoking or cut down.

Key Ingredients

Nicotine

• The main active ingredient in the Nicorette Fruitfusion lozenges is nicotine, which is delivered in a controlled manner to help relieve withdrawal symptoms.

Excipients

• The lozenges also contain small amounts of other ingredients such as sulphites, which are listed as excipients.

Mechanism of Action of Nicorette Fruitfusion 2mg Lozenges

The Nicorette Fruitfusion 2mg lozenges work as a nicotine replacement therapy (NRT) to help relieve withdrawal symptoms and cravings when quitting smoking.Controlled Nicotine Delivery

• The lozenges are designed to deliver nicotine into the system through the lining of the mouth, rather than the stomach.
• As the lozenge slowly dissolves in the mouth, nicotine is released and absorbed through the oral mucosa.
• This provides a therapeutic dose of nicotine to the body, helping to ease cravings and withdrawal symptoms associated with quitting smoking.

Craving Relief

• Clinical studies have shown that nicotine replacement products like the Nicorette lozenges can help smokers abstain from smoking by relieving withdrawal symptoms and cravings.
• The lozenges allow users to manage cravings and urges to smoke in situations where they are unable or unwilling to smoke.

Gradual Nicotine Reduction

• As the body adjusts to receiving less nicotine, users can gradually reduce the number of lozenges used until they no longer need nicotine replacement.
• This helps facilitate a smoother transition away from the dependence on nicotine from cigarettes.         Nicorette Fruitfusion 2mg Lozenges can be used during pregnancy, but with some precautions:
  • Nicotine replacement therapy (NRT) products like the Nicorette lozenges are generally considered safer than smoking during pregnancy, as they do not contain the harmful chemicals found in cigarette smoke.
  • The lozenges can help relieve withdrawal symptoms and cravings to support smoking cessation efforts. Using NRT is preferable to continuing to smoke during pregnancy.
  • Fast-acting NRT like lozenges may be the safest option, as they allow for intermittent dosing to satisfy cravings. Slow-release patches are not recommended for more than 16 hours per day.
  • Pregnant women should avoid liquorice-flavored nicotine products and opt for other flavors like fruit or mint instead.
  • It’s important to speak with a doctor, nurse or pharmacist before using NRT during pregnancy to determine the best product and dosage. The goal is to use NRT for 8-12 weeks and gradually reduce until completely nicotine-free.
  • While NRT is safer than smoking, it is not completely risk-free. The potential benefits of using NRT to quit smoking must be weighed against the risks on an individual basis.

  The chemical structure of nicotine, the active ingredient in Nicorette Fruitfusion 2mg Lozenges, is as follows:

  Molecular Formula: C10H14N2


  Nicotine is a naturally occurring alkaloid found in the nightshade family of plants, primarily tobacco. It is a colorless, volatile, and hygroscopic liquid that readily dissolves in water or alcohol.The nicotine molecule consists of a pyridine ring connected to a pyrrolidine ring. The pyridine ring contains a nitrogen atom, while the pyrrolidine ring contains two nitrogen atoms, one of which is part of the pyridine ring.The chemical structure of nicotine can be represented as:

  \ce{C9H13N+CH3I->C10H14N2I}

  where the methyl group (CH3) is attached to the nitrogen atom in the pyrrolidine ring, forming the quaternary ammonium compound.

  

  Nicotine

  Stimulant and anxiolytic chemical

  More

  Definition

  A naturally produced alkaloid in the nightshade family of plants, used recreationally and as a pharmaceutical drug for smoking cessation.

  Primary Sources

  Most predominantly found in tobacco and Duboisia hopwoodii.

  Pharmacological Role

  Acts as a receptor agonist at most nicotinic acetylcholine receptors, except at nAChRα9 and nAChRα10 where it acts as a receptor antagonist.
  The nicotine molecule contains two ring structures:

  1. Pyridine ring

  • The pyridine ring is a heterocyclic aromatic ring consisting of five carbon atoms and one nitrogen atom.
  • It is derived from niacin (nicotinic acid) during nicotine biosynthesis.

  2. Pyrrolidine ring

  • The pyrrolidine ring is a saturated heterocyclic ring consisting of four carbon atoms and one nitrogen atom.
  • It is derived from the N-methyl-Δ 1-pyrrollidium cation during nicotine biosynthesis.

  The two rings are connected via a carbon-carbon bond, forming the bicyclic structure of nicotine. The pyridine ring is attached to the 2-position of the pyrrolidine ring, with the nitrogen atom of the pyrrolidine ring being methylated.The chemical structure of nicotine can be represented as:

  \ce{C9H13N+CH3I->C10H14N2I}

  where the methyl group (CH3) is attached to the nitrogen atom in the pyrrolidine ring, forming the quaternary ammonium compound.

  

  

  

  Dosage

  • The recommended dosage for the Nicorette Fruitfusion 2mg lozenges is:
    • Most smokers require 8 to 12 lozenges per day, not to exceed 15 lozenges.
    • One lozenge should be placed in the mouth and allowed to slowly dissolve, moving it around periodically.
    • The lozenge should not be chewed or swallowed.

  Usage

  • Smokers willing or able to stop smoking immediately should initially replace all their cigarettes with the lozenges.
  • As soon as they are able, users should reduce the number of lozenges used until they have stopped completely.
  • Smokers aiming to reduce cigarettes should take the lozenges as needed between smoking episodes to prolong smoke-free intervals.

  Storage

  • The Nicorette Fruitfusion 2mg lozenges should be stored at room temperature, away from heat, moisture, and direct light.
  • The lozenges should be kept out of the reach of children.

  Reviews

  • Many users report that the Nicorette Fruitfusion lozenges are effective at relieving cravings and withdrawal symptoms when trying to quit smoking.
  • Reviewers find the fruit flavor to be pleasant and enjoy the controlled nicotine delivery.
    

    Precautions

    • Children Under 12 Years: The product is contraindicated for children under the age of 12 years due to the risk of severe toxicity from nicotine. Doses of nicotine tolerated by adult and adolescent smokers can produce severe toxicity in children that may be fatal.
    • Hypersensitivity: The product is contraindicated in individuals who are hypersensitive to any of its components.
    • Choking Hazard: The lozenges can represent a choking hazard, especially for children. They should be kept out of the reach of children and used with caution in individuals with aspiration and swallowing problems.
    • Pregnancy and Lactation: The product is indicated for use in pregnant and lactating women making a quit attempt. However, it is important to consult a doctor or pharmacist before using NRT during pregnancy.

    Contraindications

    • Children Under 12 Years: The product is contraindicated for children under the age of 12 years.
    • Hypersensitivity: The product is contraindicated in individuals who are hypersensitive to any of its components.

    Overdose

    • Overdose: The product should not be taken in excess of the recommended dose. Most smokers require 8 to 12 lozenges per day, not to exceed 15 lozenges.

    Additional Information

    • Transferred Dependence: Transferred dependence is rare and is both less harmful and easier to break than smoking dependence.
    • Stopping Smoking: When a smoker stops smoking, there may be a slower metabolism of certain drugs, which can result in higher blood levels of those drugs. This is of potential clinical importance for products with a narrow therapeutic window.