Description

Singulair 10mg 28’ct is a medication imported and sold in Pakistan for the treatment of asthma and allergy symptoms. The key points are:

• Singulair 10mg 28’ct contains the active ingredient montelukast sodium, which is used to control and prevent symptoms of asthma and allergies.
• The price of Singulair 10mg 28’ct in Pakistan is around ₨49,999.00 (approximately $180.27).
• Singulair 10mg is a prescription medication that should be taken regularly to manage asthma and allergy symptoms. It is not meant for immediate relief of acute symptoms.
• Potential side effects of Singulair 10mg include abdominal pain, headache, thirst, and rarely more serious reactions like anaphylaxis or liver injury. Patients should consult their doctor before use.
  

  Product Details

  • Singulair 10mg 28’ct is a medication imported and sold in Pakistan.
  • It contains the active ingredient montelukast sodium, which is used to control and prevent symptoms of asthma and allergies.

  Pricing

  • The price of Singulair 10mg 28’ct in Pakistan is around ₨49,999.00 (approximately $180.27).

  Usage and Precautions

  • Singulair 10mg is a prescription medication that should be taken regularly to manage asthma and allergy symptoms.
  • It is not meant for immediate relief of acute symptoms.
  • Potential side effects include abdominal pain, headache, thirst, and rarely more serious reactions like anaphylaxis or liver injury.
  • Patients should consult their doctor before use.

  Key Benefits of Singulair 10mg 28’ct in Pakistan:

  1. Asthma Prevention: Reduces and prevents swelling and inflammation in the lungs, making breathing easier.
  2. Allergy Relief: Relieves symptoms of allergic rhinitis (runny nose, sneezing, chest congestion, itching, watery eyes, and stuffy nose).
  3. Exercise-Induced Asthma Prevention: Helps prevent breathing problems during exercise.

  Key Ingredients:

  1. Montelukast Sodium: The active ingredient that blocks leukotrienes, reducing inflammation and improving asthma symptoms.

  Side Effects:

  • Common: Headache, abdominal pain, diarrhea, and nausea.
  • Rare: Anaphylaxis, angioedema, seizure, elevated liver enzymes, and gastrointestinal upset.

  Precautions:

  • Pregnancy and Breastfeeding: Use with caution and consult a doctor.
  • Alcohol: Avoid consuming alcohol while taking Singulair.
  • Driving: Avoid driving if you experience dizziness or drowsiness.

  Usage:

  • Dosage: One 10mg tablet daily, taken with or without food.
  • Duration: Take as directed by your doctor, and do not stop taking it without consulting your doctor.

  Price in Pakistan:

  • Approximate Price: ₨49,999.00 (approximately $180.27).

  Storage:

  • Room Temperature: Store at room temperature in a cool dry place.

  Interactions:

  • Other Medications: Inform your doctor about all other medications you are taking before starting Singulair.

  Contraindications:

  • Increased Eosinophils: Not recommended for patients with increased eosinophils in the blood.

  Safety Advice:

  • Neuropsychiatric Events: Monitor for behavior and mood-related changes, such as agitation, aggression, irritability, restlessness, and suicidal thinking.

  Product Summary:

  • Offer Price: ₹110.08 (approximately $1.43).
  • Contains: Montelukast (10.0 mg).

  Other Products:

  • Montair 10mg: By Cipla Limited, 15 tablets in a strip.
  • Odimont 10mg: By Zydus Healthcare Limited, 10 tablets in a strip.
  • Montek 10mg: By Sun Pharma, 10 tablets in a strip.
  • Montemac 10mg: By Macleods Pharmaceuticals, 10 tablets in a strip.

  Manufacturer:

  • Getz Pharma: You save 61.28% Rs.36/tablet.
  • Barrett: You save 63.13% Rs.34.29/tablet.
  • Genix: You save 62.36% Rs.35/tablet.
  • GT Pharma: You save 66.66% Rs.31/tablet.

  Other Brands:

  • Martin Dow: You save 61.59% Rs.35.71/tablet.
  • AGP: You save 56.44% Rs.40.5/tablet.
  • Siza: You save 84.71% Rs.14.21/tablet.
  • Macter: You save 75.73% Rs.22.57/tablet.
  • Himont: You save 76.19% Rs.22.14/tablet.
  • Novartis: You save 76.19% Rs.22.14/tablet.
  • Le Mendoza: You save 83.87% Rs.15/tablet.
  • Libra: You save 80.64% Rs.18/tablet.
  • Highnoo: You save 79.64% Rs.18.93/tablet.

  Mechanism of Action of Singulair (Montelukast)Singulair (montelukast) is a leukotriene receptor antagonist that works by blocking the action of leukotrienes, which are chemical messengers that cause narrowing and swelling of airways in the lungs and also trigger allergy symptoms.Specifically, montelukast blocks the cysteinyl leukotriene CysLT1 receptor. Leukotrienes are potent inflammatory mediators that are released from various cells, including mast cells and eosinophils.By blocking the action of leukotrienes, montelukast:

  • Reduces inflammation in the airways, preventing asthma symptoms
  • Helps control asthma by making breathing easier
  • Improves seasonal allergy symptoms like runny nose, sneezing, and itchy/watery eyes

  Montelukast is effective in controlling asthma symptoms and preventing exercise-induced bronchoconstriction. It is also used to relieve symptoms of allergic rhinitis.The medication is taken orally once daily, typically in the evening. It can be taken with or without food. Montelukast works best when taken regularly as prescribed, even when asymptomatic, to maintain control of asthma and allergy symptoms.                                                                                                                                 

  
  
  

  Montelukast

  Medication for asthma maintenance treatment

  More

  Uses

  Maintenance treatment of asthma, allergic rhinitis, and long-duration hives

  Brand Names

  Singulair, others

  Drug Class

  Leukotriene receptor antagonist

  Chemical Structure of Montelukast

  The chemical structure of montelukast, the active ingredient in Singulair 10mg, is as follows:\ce{C35H36ClNO3S}Key structural features:

  • Montelukast is a synthetic organic compound with a molecular weight of 586.19 g/mol.
  • It contains a quinoline ring system, a phenyl ring, and a cyclopropyl carboxylic acid moiety.
  • The chlorine atom is attached to the quinoline ring.
  • It has two chiral centers, making it a racemic mixture of two enantiomers.
  • Montelukast is a lipophilic compound with a high partition coefficient (clogP = 8.8), indicating good solubility in non-polar solvents.
  • The pKa values are 2.8 (acidic) and 5.7 (basic), suggesting it can exist in both protonated and deprotonated forms depending on the pH.

  The structure of montelukast sodium, the salt form used in pharmaceutical formulations, is similar but with a sodium cation attached.

  Dosage:

  • The recommended dosage of Singulair 10mg in Pakistan is:
    • Adults and adolescents 15 years and older: One 10mg tablet once daily, typically in the evening.
    • Children 6-14 years: One 5mg chewable tablet once daily, typically in the evening.
    • Children 2-5 years: One 4mg chewable tablet or one packet of 4mg oral granules once daily, typically in the evening.
  • Singulair should be taken regularly, even when asymptomatic, to maintain control of asthma and allergy symptoms.
  • It should be taken at least 2 hours before exercise if used to prevent exercise-induced bronchoconstriction.
  • Do not take an additional dose within 24 hours of the previous one.

  Storage:

  • Singulair 10mg 28’ct should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Protect from light and moisture. Keep the medication in the original package.
  • Do not store above 30°C (86°F) or in the refrigerator.
  • Keep out of reach of children.

  Reviews:Singulair 10mg 28’ct has generally positive reviews in Pakistan for its effectiveness in managing asthma and allergy symptoms. Patients report good control of symptoms with regular use. However, some users have experienced side effects like headaches, abdominal pain, and diarrhea. It’s important to follow the dosage instructions carefully and report any adverse reactions to the doctor.

  Dietary Considerations for Singulair

  Food Interactions:

  • Singulair can be taken with or without food. There are no known interactions between Singulair and specific foods.

  Alcohol Consumption:

  • The search results do not mention any interactions between Singulair and alcohol. However, it is generally recommended to avoid or limit alcohol consumption when taking any medication, as alcohol can potentially increase side effects.

  Specific Food Preparations:

  • For the Singulair 4mg oral granules formulation, the granules can be mixed with a small amount of cold or room temperature baby formula, breast milk, or soft foods like applesauce, carrots, rice, or ice cream.
  • The oral granules should not be stored if mixed with food or liquid, and the full dose must be administered within 15 minutes of mixing.
  • Other than these specific instructions for the oral granules, the search results do not indicate any dietary restrictions or special food preparation requirements for Singulair tablets or chewables.

  Administration of Singulair Oral Granules for Children

  Dosage:

  • Children 12-23 months: One 4mg oral granule packet once daily
  • Children 2-5 years: One 4mg chewable tablet or one 4mg oral granule packet once daily
  • Children 6-14 years: One 5mg chewable tablet once daily

  Administration Options:
  The Singulair 4mg oral granules can be administered in the following ways:

  1. Directly into the child’s mouth
  2. Dissolved in 5mL (1 teaspoon) of cold or room temperature baby formula or breast milk
  3. Mixed with a spoonful of cold or room temperature soft foods like:
     • Applesauce
     • Mashed carrots
     • Rice
     • Ice cream

  Important Instructions:

  • The packet should not be opened until ready to use.
  • After opening the packet, the full dose (whether given directly, dissolved, or mixed with food) must be administered within 15 minutes.
  • The oral granules must not be stored if mixed with baby formula, breast milk, or food. Any unused portion should be discarded.
  • The oral granules should not be dissolved in any liquid other than baby formula or breast milk.
  • Singulair oral granules can be given with or without food.

  Nursing Considerations:

  • All patients should have a short-acting bronchodilator available for rescue treatment.
  • Patients and caregivers should be counseled on the risk of serious neuropsychiatric events and monitored for changes in behavior.