Description

Dapsone 100mg Tablets (1000 count)

• Used to treat leprosy and certain skin conditions
• Typical adult dosage as directed by doctor
• Swallow tablets whole, do not cut or crush
• Possible side effects include rash, nausea, fever
• Caution in liver/kidney disease, not for children under 6
• Available in 1000-count bottles, current price around ₹396                                                                    In pregnancy                                                                                                                                 Dapsone appears relatively safe for use during pregnancy, though more data is needed. Animal studies have not shown increased risk of birth defects. Doctors must weigh potential benefits versus risks when prescribing dapsone for pregnant women.
  

  Dapsone

  Antibiotic commonly used to treat leprosy and other skin conditions

  More

  Trade names

  Aczone, others

  Common uses

  Treatment of leprosy, acne, dermatitis herpetiformis

  Side effects

  May include decrease in blood cells, liver inflammation, skin rashes

  The primary mechanism of action for dapsone is:Dapsone acts as an antibacterial agent by inhibiting the synthesis of dihydrofolic acid in susceptible bacteria. It does this by competing with para-aminobenzoate for the active site of the enzyme dihydropteroate synthase, which is involved in the folate synthesis pathway.In addition to its antibacterial effects, dapsone also has anti-inflammatory and immunosuppressive properties, though the exact mechanisms for these actions are not fully understood.Dapsone is primarily used to treat leprosy, dermatitis herpetiformis, and other skin conditions. It is also used as a second-line treatment for pneumocystis pneumonia and toxoplasmosis in immunocompromised patients.

  Key Benefits

  • Treats leprosy (a bacterial skin and nerve infection) in combination with other medications 
  • Treats dermatitis herpetiformis, a chronic itchy skin rash with blisters caused by an overactive immune system 
  • Also used as a second-line treatment for pneumocystis pneumonia and toxoplasmosis in immunocompromised patients 

  The key ingredient in dapsone 100mg tablets is:

  • Dapsone (100mg per tablet)

  Other inactive ingredients include:

  • Colloidal silicone dioxide
  • Magnesium stearate
  • Microcrystalline cellulose
  • Corn starch
  • Lactose monohydrate
  • Maize starch
  • Sodium laurilsulfate
  • Colloidal anhydrous silica

  Reviews

  • For dermatitis herpetiformis, a user reported that dapsone has worked great without any known side effects. They found they needed much less than the usual 100mg dose, around 25-50mg, to effectively control their symptoms.
  • For leukocytoclastic vasculitis, a user said dapsone “saved me from pain” along with prednisone, and seems to work on a 24-hour cycle – if they miss a dose, the painful welts return.