Description

Product Overview

Kreon 10,000 IU capsules are a dietary supplement that provides a concentrated dose of pancreatic enzymes, particularly lipase, to aid in the digestion of fats. They are primarily used to treat pancreatic exocrine insufficiency, a condition that can occur due to various factors such as cystic fibrosis, chronic pancreatitis, or other digestive disorders.

Key Features

• Manufactured by Abbott Laboratories in Pakistan
• Each bottle contains 100 capsules
• Suitable for mild to moderate digestive enzyme deficiencies
• Helps break down fats, carbohydrates, and proteins for efficient nutrient absorption
• Provides lipase to target fats, protease for proteins, and amylase for carbohydrates
  

  Key Benefits of Kreon 10,000 IU Capsules

  Improved Digestion and Nutrient Absorption
  The pancreatic enzymes in Kreon 10,000 IU, including lipase, protease, and amylase, help break down fats, proteins, and carbohydrates in food. This allows for more efficient digestion and better absorption of essential nutrients.Relief from Digestive Discomfort
  By addressing pancreatic enzyme deficiencies, Kreon 10,000 IU can help alleviate symptoms like gas, bloating, abdominal pain, and diarrhea associated with conditions like pancreatic exocrine insufficiency.Supports Overall Digestive Health
  Kreon 10,000 IU promotes healthy digestive function, which is crucial for maintaining overall well-being and energy levels.

  Key Ingredients in Kreon 10,000 IU Capsules

  Pancreatin
  The primary active ingredient in Kreon 10,000 IU is pancreatin, a mixture of digestive enzymes derived from the pancreas of pigs. This includes:

  • Lipase: Breaks down fats
  • Protease: Breaks down proteins
  • Amylase: Breaks down carbohydrates

  Other Inactive Ingredients
  The capsules also contain the following inactive ingredients:

  • Hypromellose
  • Titanium dioxide
  • Triacetin

  Mechanism of Action of Kreon 10,000 IU Capsules

  Kreon 10,000 IU capsules contain a blend of pancreatic enzymes that work together to aid in the digestion of fats, proteins, and carbohydrates. The key mechanisms of action are:Lipase Activity
  The lipase enzyme in Kreon 10,000 IU helps break down fats (triglycerides) into smaller fatty acids and monoglycerides. This allows for more efficient absorption of fat-soluble vitamins and other nutrients.Protease Activity
  The protease enzymes in Kreon 10,000 IU break down proteins into smaller peptides and amino acids. This facilitates the absorption of protein-derived nutrients.Amylase Activity
  The amylase enzyme in Kreon 10,000 IU converts complex carbohydrates into simpler sugars that can be more readily absorbed by the body.By providing these key digestive enzymes, Kreon 10,000 IU helps compensate for pancreatic exocrine insufficiency, a condition where the pancreas does not produce enough of its own digestive enzymes. This allows for improved digestion and absorption of nutrients from the diet.The timing of taking Kreon 10,000 IU is important, as the enzymes need to be present in the digestive tract at the same time as the food being consumed. This ensures the enzymes can effectively break down the nutrients.

  
  

  Warnings and Precautions

  1. Severe Allergic Reactions: Kreon may cause serious allergic reactions like anaphylaxis, characterized by symptoms such as wheezing, trouble breathing, rapid heartbeat, and fainting. If you experience any of these symptoms, seek immediate medical help.
  2. Lung Irritation: Inhaling Kreon powder can irritate your lungs, leading to coughing, wheezing, and difficulty breathing. To avoid this, take Kreon with plenty of fluids and be careful not to inhale the powder.
  3. High Uric Acid Levels: Kreon may increase uric acid levels in your blood, which could trigger gout attacks if you’re susceptible. If you have a history of gout or high uric acid, closely monitor your levels while taking Kreon and discuss any concerns with your doctor.
  4. Increased Bowel Movements and Gas: You may experience increased bowel movements and gas, particularly when starting Kreon or at higher doses. These effects usually improve over time, but if they’re bothersome, consult your doctor.

  Additional Precautions

  1. Timing: It’s best to take Kreon with meals and snacks for maximum effectiveness. If you miss a dose, don’t double up; just take the next dose as usual.
  2. Food Interactions: Certain foods and medications might interact with Kreon. Inform your doctor about all the medicines and dietary supplements you are taking.
  3. Children: While Kreon is safe for children, the dosage varies based on age and weight. Always consult a doctor for the correct dosage.
  4. Pregnancy and Breastfeeding: If you’re pregnant or breastfeeding, talk to your doctor before starting Kreon as its safety during these periods is not fully established.
  5. Avoiding Irritation: Do not hold the Kreon capsules or their contents in your mouth, and do not store any mixture made with the granules for later use. This is to avoid mouth irritation and ensure the medicine works effectively.

  Interactions with Medications

  • Kreon may interact with certain medications, so it’s important to inform your doctor about all the prescription, over-the-counter, and supplement products you are taking.
  • Specific medications that may interact with Kreon include:
    • Acarbose and miglitol – These diabetes medications may be affected by Kreon.
    • Antacids like calcium carbonate – These can impact the effectiveness of Kreon.
  • To minimize interactions, your doctor may recommend specific timing for taking antacids or other medications in relation to when you take Kreon.

  Interactions with Supplements

  • Supplements like sodium bicarbonate may also interact with Kreon and affect its effectiveness.
  • It’s recommended to discuss the use of any herbal supplements or vitamins with your doctor before taking them with Kreon.

  Other Considerations

  • There are no specific reports of Kreon interacting with vaccines or laboratory tests, but it’s still advisable to consult your doctor for guidance.
  • The use of cannabis with Kreon is also something you should discuss with your healthcare provider, as the combination could impact your treatment plan.

  Acidic Foods

  It is recommended to mix the granules from the Kreon capsules with acidic liquids like apple, orange, or pineapple juice if you prefer not to swallow the capsules whole. This helps dissolve the granules and facilitates absorption in the body.

  High-Fat or High-Protein Meals

  If you are consuming meals that are particularly high in fat or protein, a higher dose of Kreon may be needed, such as the 25,000 IU formulation. Consult with your healthcare provider to determine the appropriate dosage based on your specific dietary intake.

  Timing of Meals

  It is important to take Kreon 10,000 IU at the same time as meals or snacks for maximum effectiveness. The enzymes need to be present in the digestive tract along with the food being consumed in order to properly break down the nutrients.

  Acidic vs Non-Acidic Foods

  Avoid mixing the Kreon granules with non-acidic foods or liquids, as this can lead to mouth irritation and alter the way the medication works. Swallow the mixture right away without chewing.

  Hydration

  Drink plenty of fluids throughout the day when taking Kreon 10,000 IU. Staying well-hydrated supports healthy digestion and prevents constipation.

  Dosage and Administration

  • Kreon 10,000 IU capsules are typically taken with each meal or snack, as directed by your doctor.
  • The recommended dosage varies based on the patient’s age, weight, and severity of pancreatic enzyme deficiency.
  • For adults and children over 12 months, the capsules can be swallowed whole with plenty of liquid or the contents can be sprinkled on acidic soft foods like applesauce.
  • For infants under 12 months, the capsule contents can be sprinkled directly into the mouth or mixed with a small amount of room temperature applesauce, then followed by breast milk or formula.
  • If a dose is missed, skip it and resume the regular dosing schedule with the next meal or snack. Do not double up on doses.

  Storage

  • Store Kreon 10,000 IU capsules at room temperature, away from heat, moisture, and direct light.
  • Keep the capsules in their original container with the desiccant packet to protect them from moisture.
  • Discard any mixture made with the capsule contents and do not store it for later use.

  Reviews

  • Kreon 10,000 IU capsules have generally positive reviews from patients who report improved digestion and reduced gastrointestinal symptoms when taken as directed.
  • Some users note experiencing less bloating, gas, and diarrhea after starting Kreon.
  • A few reviewers mention the capsules are easy to swallow and the dosage is convenient to take with meals.

  Use During Pregnancy

  • Pancreatic enzymes like those in Kreon can be used during pregnancy if required, but should be taken in doses sufficient to provide adequate nutrition and control digestive symptoms.
  • The safety of Kreon during pregnancy has not been fully established, so it is important to consult with a doctor before using it while pregnant.

  Use During Breastfeeding

  • Pancreatic enzymes can be used during breastfeeding.
  • If Kreon is required while breastfeeding, it should be used in doses sufficient to provide adequate nutrition and control digestive symptoms.
  • When administering Kreon to infants under 12 months old, the capsule contents can be sprinkled directly into the mouth or mixed with a small amount of room temperature applesauce, then followed by breast milk or formula.