Description

Indications

Acromegaly

Sandostatin LAR is primarily used to treat acromegaly, a disorder characterized by excessive growth hormone production. Symptoms include enlarged hands and feet, coarsening of facial features, and fatigue.

Gastrointestinal Tumors

It is also indicated for managing symptoms associated with certain gastrointestinal tumors, such as carcinoid tumors and VIPoma, which can cause severe diarrhea and flushing.

Mechanism of Action

Sandostatin LAR mimics somatostatin, a natural hormone that regulates hormone release in the body. By inhibiting excess growth hormone and hormone production from tumors, it helps alleviate symptoms and control tumor growth.

Dosage and Administration

• Starting Dose: 20mg administered intramuscularly every 4 weeks.
• Dosage Adjustments: After 2 months, the dose may be adjusted based on symptom control, with options to reduce to 10mg or increase to 30mg if necessary.
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