Description

Temoside 100mg 5’ct capsules are a medication used to treat various types of cancer, including glioblastoma multiforme and anaplastic astrocytoma. The capsules contain 100mg of temozolomide, which is a hazardous drug that requires special handling and disposal procedures. The recommended dosage for Temoside 100mg 5’ct capsules is 100mg per square meter (m²) of body surface area, taken orally once daily for a maximum of 42 to 49 days in combination with focal radiotherapy for treating certain types of brain cancer. Temoside 100mg 5’ct capsules are prescribed to treat brain cancer and should be taken as directed by a doctor. Patients should not stop taking the medication without consulting their healthcare provider.

Unique Information

• Imported medication
• Contains 100mg of temozolomide per capsule
• Comes in a package of 5 capsules

Indications

• Glioblastoma multiforme
• Anaplastic astrocytoma

Dosage

• 100mg per square meter (m²) of body surface area
• Taken orally once daily
• For a maximum of 42 to 49 days
• In combination with focal radiotherapy for certain brain cancers

Important Notes

• Temozolomide is a hazardous drug that requires special handling and disposal procedures
• Patients should not stop taking the medication without consulting their healthcare provider

Key Benefits:

• Used to treat various types of brain cancer, including glioblastoma multiforme and anaplastic astrocytoma 
• Works by killing cancer cells and preventing their growth and spread 
• Can be used in combination with focal radiotherapy to treat certain brain cancers 

Key Ingredient:

• Contains 100mg of temozolomide per capsule 
• Temozolomide is a hazardous anti-cancer drug that requires special handling and disposal procedures 

The key benefits of Temoside 100mg 5’ct capsules are that they are used to treat various types of brain cancer, including glioblastoma multiforme and anaplastic astrocytoma, by killing cancer cells and preventing their growth and spread. The capsules can be used in combination with focal radiotherapy to treat certain brain cancers. The key ingredient is 100mg of temozolomide per capsule, which is a hazardous anti-cancer drug that requires special handling and disposal.

Mechanism of Action of Temoside 100mg Capsules

The active ingredient in Temoside 100mg capsules is temozolomide, which is an alkylating agent that works by inhibiting DNA synthesis and cell division in cancer cells.The mechanism of action of temozolomide is as follows:Activation to MTIC

• Temozolomide is a prodrug that is converted to the active metabolite 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC) at physiological pH.
• MTIC is the key cytotoxic species that mediates the anti-tumor effects of temozolomide.

DNA Alkylation and Damage

• MTIC alkylates DNA, primarily at the O6 position of guanine and the N7 position of guanine.
• This DNA alkylation leads to DNA strand breaks and inhibits DNA replication and cell division.

Inhibition of Cell Growth and Division

• The DNA damage caused by temozolomide’s alkylation ultimately leads to cell cycle arrest and apoptosis (programmed cell death) in cancer cells.
• This prevents the growth and division of cancer cells, thereby inhibiting tumor progression.

Dosage

• The recommended dosage of Temoside 100mg capsules is 150-200mg/m2 of body surface area, taken orally once daily.
• The dosage is typically taken on an empty stomach, either 1 hour before or 2 hours after a meal.
• The duration of treatment is usually 42-49 days, in combination with focal radiotherapy for certain brain cancers.
• Dosage adjustments may be required based on individual patient response and tolerability.

Storage

• Temoside 100mg capsules should be stored below 25°C, in a cool and dry place.
• Keep the capsules away from light, heat, and moisture.
• Store the medication out of the reach of children.

Reviews of Temoside 100mg Capsules

Based on the available information:

• Temoside 100mg capsules are an effective treatment for certain types of brain cancer, such as glioblastoma multiforme and anaplastic astrocytoma.
• The medication has been shown to improve progression-free survival and overall survival in patients with these aggressive brain tumors.
• Common side effects include nausea, vomiting, fatigue, headache, and myelosuppression (low blood cell counts).
• Patients generally tolerate the medication well when taken as directed by their oncologist.
• Regular monitoring of blood counts and other laboratory parameters is necessary during treatment with Temoside.