Key Benefits of Amphotericin B 50mg Injection in Pakistan

1. Treats serious, potentially fatal fungal infections:
   • Amphotericin B is used to treat a wide range of systemic fungal infections, including aspergillosis, cryptococcosis, candidiasis, and other serious fungal infections.
2. Effective against drug-resistant fungi:
   • Amphotericin B has a low incidence of drug resistance, making it an effective treatment option for severe fungal infections.
3. Used for life-threatening protozoan infections:
   • In addition to fungal infections, amphotericin B is also used to treat serious protozoan infections like visceral leishmaniasis and primary amoebic meningoencephalitis.
4. Available in Pakistan at affordable prices:
   • Amphotericin B 50mg injection is available in Pakistan, with prices ranging from Rs. 618 to Rs. 20,000 depending on the brand.
   • The generic brand Amphotret costs around Rs. 1,000, making it accessible for patients.
5. Approved by regulatory authorities:
   • Amphotericin B is an FDA-approved antifungal medication and is included on the World Health Organization’s List of Essential Medicines.

Key Ingredients in Amphotericin B 50mg Injection

1. Amphotericin B: The active pharmaceutical ingredient, which is a potent antifungal medication. Each vial contains 50 mg of amphotericin B.
2. Sodium Desoxycholate: A solubilizing agent that helps dissolve the insoluble amphotericin B to form a colloidal dispersion for intravenous infusion.
3. Sodium Phosphates: A buffering system consisting of dibasic and monobasic sodium phosphates, phosphoric acid, and sodium hydroxide. This helps maintain the pH of the solution.
4. Nitrogen: The air in the vial is replaced with nitrogen gas during manufacturing.

The key inactive ingredients are:

• Deoxycholic acid (38.75 mg per 10 mL)
• Dibasic sodium phosphate (18.85 mg per 10 mL)
• Monobasic sodium phosphate monohydrate (1.02 mg per 10 mL)
• Phosphoric acid and sodium hydroxide (used for pH adjustment)