Description

GNC Chromium Picolinate 200 mcg is a dietary supplement that contains the mineral chromium in the form of chromium picolinate. It is imported from the USA and sold in Pakistan.The key details about this product are:

• It contains 200 mcg of chromium picolinate per serving, which is the recommended daily intake of chromium.
• It is packaged in bottles of 90 tablets.
• The product is imported from the USA and sold in Pakistan.
• Prices for this product in Pakistan range from around ₨3,600 to ₨6,000 depending on the retailer.
• The supplement is marketed as supporting glucose utilization and energy release in the body.
  

  Product Details

  • Contains 200 mcg of chromium picolinate per serving
  • Packaged in bottles of 90 tablets
  • Imported from the USA and sold in Pakistan

  Pricing in Pakistan

  • Prices range from approximately ₨3,600 to ₨6,000 depending on the retailer

  Key Benefits of GNC Chromium Picolinate 200 mcg

  Supports Glucose Utilization and Energy Release

  • Chromium plays an important role in glucose utilization and is required for the release of energy from glucose

  Helps Maintain Healthy Blood Sugar Levels

  • Chromium is an essential trace mineral that helps insulin regulate blood glucose levels
  • It may help maintain healthy blood sugar levels within a normal range

  Useful for Treating Type 2 Diabetes

  • Chromium has been shown to be useful in treating type 2 diabetes in several ways, including improving glucose tolerance

  Key Ingredients

  The key ingredient in this supplement is:

  • Chromium Picolinate – Provides 200 mcg of chromium per serving, which is the recommended daily intake

  The other ingredients are:

  • Dicalcium Phosphate – A mineral used as a filler and binder
  • Cellulose – A plant-derived fiber used as a filler and binder

  The product is free of common allergens and additives like sugar, artificial colors, flavors, and preservatives.

  How Chromium Picolinate Improves Glucose Tolerance

  Supports Glucose Utilization and Energy Release

  • Chromium plays an important role in glucose utilization and is required for the release of energy from glucose .

  Helps Maintain Healthy Blood Sugar Levels

  • Chromium is an essential trace mineral that helps insulin regulate blood glucose levels .
  • Chromium supplementation may help maintain healthy blood sugar levels within a normal range .

  Useful for Treating Type 2 Diabetes

  • Chromium has been shown to be useful in treating type 2 diabetes in several ways, including improving glucose tolerance .

  However, the research on the effects of chromium picolinate supplementation on glucose tolerance and insulin sensitivity is mixed:

  • Some studies have found benefits of chromium supplementation for glycemic control in those with type 2 diabetes .
  • Other studies, including a randomized controlled trial, found no significant improvements in glucose levels, insulin levels, or insulin resistance with chromium picolinate supplementation in those at risk for diabetes .

  The inconsistent findings may be due to factors like the duration of supplementation, the specific chromium formulation used, the dosage, and the baseline health status of the study participants . More research is still needed to fully understand the potential glucose-regulating effects of chromium picolinate.

  How Chromium Picolinate Supports Weight Loss

  1. Appetite Suppression: Chromium picolinate can reduce appetite and eating compulsions, leading to a decreased overall calorie intake.
  2. Improved Insulin Sensitivity: Chromium picolinate helps stabilize blood sugar levels by facilitating insulin action, which can aid in weight loss by reducing insulin resistance and improving glucose metabolism.
  3. Lean Body Mass Preservation: Chromium picolinate has been shown to help maintain lean body mass during weight loss, which is important for overall health and metabolism.
  4. Reduced Fat Mass: Studies have found that chromium picolinate supplementation can lead to significant reductions in body fat mass while maintaining lean body mass.

  Key Studies and Findings

  1. Weight Loss in Overweight Adults: A meta-analysis of nine randomized controlled trials found that chromium picolinate supplementation resulted in a small but significant weight loss of approximately 1 kg compared to placebo.
  2. Body Composition Changes: Another study found that chromium picolinate supplementation resulted in a greater loss of body fat and a preservation of lean body mass compared to diet alone.

  Potential Side Effects and Contraindications

  1. Common Side Effects: Headache, insomnia, diarrhea, nausea, stomach pain, vomiting, liver problems, and anemia are possible side effects.
  2. Contraindications: Chromium picolinate should not be used by children under 12, those with kidney failure, severe liver disease, thyroid problems, or those allergic to picolinic acid or chromium.

  Conclusion

  Chromium picolinate can be a helpful supplement for those seeking to manage their weight, particularly by reducing appetite and improving insulin sensitivity. However, it is essential to consult a healthcare professional before using this supplement and to maintain a balanced diet and regular exercise regimen for optimal results.                                                                                                 

  Mechanism of Action of Chromium Picolinate

  Based on the search results, the key mechanisms by which chromium picolinate supports health and weight management are:Enhances Insulin Action

  • Chromium (III) is an essential trace mineral that enhances insulin action, thereby influencing carbohydrate, lipid, and protein metabolism .
  • Chromium plays an important role in glucose utilization and is required for the release of energy from glucose .

  Supports Healthy Glucose Metabolism

  • Chromium helps insulin regulate blood glucose levels and may help maintain healthy blood sugar levels within a normal range .
  • Chromium has been shown to be useful in treating type 2 diabetes, including by improving glucose tolerance .

  Protects Against Iron-Induced Glucose Metabolism Abnormalities

  • Chromium may have a protective effect on iron-induced glucose metabolism abnormalities through the ROS-mediated PI3K/Akt/GLUT4 signaling pathway
    
    

    Chemical Structure of Chromium Picolinate

    Based on the search results, the chemical structure of chromium picolinate can be summarized as follows:Molecular Formula
    The molecular formula of chromium picolinate is C18H12CrN3O6, which can be written as Cr(C5H4NO2)3.Structural Features

    • Chromium(III) (Cr3+) is the central metal ion.
    • Three picolinate ligands (C5H4NO2-) coordinate to the Cr3+ center in a distorted octahedral geometry.
    • Each picolinate ligand acts as a bidentate chelating agent, coordinating through the carboxylate oxygen and the pyridine nitrogen.
    • The Cr-O bond length is around 1.949-1.957 Å, and the Cr-N bond length is around 2.047-2.048 Å.
    • The compound has a pinkish-red color.

    Charge and Coordination

    • The overall charge of the chromium picolinate complex is neutral, with the three picolinate ligands neutralizing the +3 charge of the Cr3+ center.
    • The coordination number of the Cr3+ center is 6, with the three picolinate ligands providing a total of six coordination sites.
    
    

    

  Dosage

  • The recommended dosage is 1 caplet per day.
  • Each caplet contains 200 mcg of chromium as chromium picolinate.

  Storage

  • Store in a cool, dry place.
  • Keep out of reach of children.
  • Consult a healthcare professional before use, especially if you have a medical condition or are taking medications.

  Reviews of GNC Chromium Picolinate 200 mcg

  The search results do not contain any specific reviews of this product. However, some general information about chromium picolinate supplements can be inferred:

  • Chromium picolinate has been shown to be useful in treating type 2 diabetes in several ways, including improving glucose tolerance.
  • Chromium plays an important role in glucose utilization and is required for the release of energy from glucose.
  • Chromium is an essential trace mineral that helps insulin regulate blood glucose levels.

  Key Precautions

  Consult a Healthcare Practitioner

  • Consult a health care practitioner prior to use if you have a kidney disorder and/or diabetes .
  • Do not use if you are pregnant or breastfeeding .

  Sealed for Safety

  • This package is sealed for safety. Do not use if the safety seal is broken or missing .