Description

Imodium Liqui-Gels, specifically the 24- and 36-count capsules available in Canada, contain 2 mg of loperamide hydrochloride per capsule, which is a synthetic piperidine derivative that acts as a long-acting antidiarrheal agent by slowing intestinal motility to reduce diarrhea symptoms127. The capsules are liquid-filled, clear blue, oval-shaped, and non-printed, formulated for fast and soothing relief

Unique and important information includes:

• Formulation and Appearance: The capsules contain a liquid fill, which helps provide rapid onset of action compared to tablets. The distinctive clear blue, oval-shaped, non-printed design differentiates them from other dosage forms13.

• Inactive Ingredients: The formulation includes FD&C blue No. 1, gelatin, glycerol, propylene glycol, propylene glycol monocaprylate, soya lecithin, triglycerides, and water, which together stabilize the liquid fill and aid in absorption23.

• Pharmacokinetics: Loperamide has a half-life of about 11 hours (range 9-14 hours), is primarily excreted unchanged in feces, and is not significantly absorbed systemically, which limits central nervous system effects1.

• Usage Restrictions and Safety: Imodium Liqui-Gels are indicated for adults and children 12 years and older, with specific warnings against use in cases of bloody or black stools, fever, constipation, abdominal pain, or suspected bacterial infections in the bowel. Overuse can cause serious heart problems or death3.

• Storage: The product should be stored at room temperature (15-30°C) and protected from light13.

• Manufacturing and Regulation: Manufactured by McNeil Consumer Healthcare, a Johnson & Johnson division in Canada, the product meets Canadian health regulations and is available in blister packs of various sizes including 6, 12, 24, 36, and 60 capsules