Description

Cladribine 10mg/10ml Injection is a synthetic antineoplastic agent used primarily for the treatment of certain types of cancer, most notably hairy cell leukemia and B-cell chronic lymphocytic leukemia. It is administered via continuous intravenous infusion, typically under the supervision of a qualified healthcare professional experienced in antineoplastic therapy.

Key Features:

• Composition: Each milliliter contains 1 mg of cladribine, a chlorinated purine nucleoside analogue.

• Administration: Given as a continuous intravenous infusion, usually for 7 consecutive days at a dose of 0.09 mg/kg/day for hairy cell leukemia.

• Indications:

  • Hairy Cell Leukemia: Effective in treating this rare form of blood cancer.

  • B-cell Chronic Lymphocytic Leukemia (CLL): Used for patients who have not responded to or have progressed after standard treatments.

• Mechanism of Action: Interferes with DNA and RNA synthesis in cancer cells, preventing their growth and multiplication.

• Side Effects: Common side effects include nausea, fatigue, headache, rash, and suppression of blood cells, which can increase susceptibility to infections or bleeding. Serious side effects can include neurotoxicity and nephrotoxicity, especially at high doses.